Well, the point about suicide was that you wouldn't have time to repent afterwards, iirc.
And if 'holy spirit' here meant 'wisdom' or 'conscience', and the sin was refusing to EVER listen to wisdom/conscience, then you'd be pretty much screwed. (And, again, wouldn't have the wisdom to repent.)
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And if 'holy spirit' here meant 'wisdom' or 'conscience', and the sin was refusing to EVER listen to wisdom/conscience, then you'd be pretty much screwed. (And, again, wouldn't have the wisdom to repent.)